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Bolg do Buckeridge

Bolg do Prof. Marcos Buckeridge - Vários artigos interessantes sobre bioetanol e afins...

Visite: http://msbuckeridge.wordpress.com/

Nitric oxide formation is inversely related to serum levels of antiangiogenic factors soluble fms-like tyrosine kinase-1 and soluble endogline in preeclampsia

Hypertension. 2008; 52(2):402-7.

Sandrim VC, Palei AC, Metzger IF, Gomes VA, Cavalli RC, Tanus-Santos JE.

Deficient NO formation has been implicated in hypertensive disorders of pregnancy. However, no previous study has compared the circulating nitrite concentrations in healthy pregnant women with those found in hypertensive disorders of pregnancy. Moreover, 2 antiangiogenic factors produced in the placenta (soluble fms-like tyrosine kinase-1 and soluble endogline) may affect NO formation during pregnancy. Here, we hypothesized that lower concentrations of markers of NO formation exist in hypertensive disorders of pregnancy and that inverse relationships exist between these markers and soluble fms-like tyrosine kinase-1 or

Comparative assessment of matrix metalloproteinase (MMP)-2 and MMP-9, and their inhibitors, tissue inhibitors of metalloproteinase (TIMP)-1 and TIMP-2 in preeclampsia and gestational hypertension.

Clin Biochem. 2008; 41(10-11):875-80

 Palei AC, Sandrim VC, Cavalli RC, Tanus-Santos JE.

OBJECTIVES: To compare the circulating levels of matrix metalloproteinase (MMP)-2, MMP-9, tissue inhibitors of metalloproteinase (TIMP)-1, TIMP-2, and the MMP-9/TIMP-1 and MMP-2/TIMP-2 ratios in preeclampsia and gestational hypertension with those found in normotensive pregnancies. DESIGN AND METHODS: We studied 83 pregnant women (30 healthy pregnant women with uncomplicated pregnancies, 26 with gestational hypertension, and 27 with preeclampsia) and 30 healthy nonpregnant women in a

Haplotypes of vitamin D receptor modulate the circulating levels of lead in exposed subjects.

Arch Toxicol. 2008; 82(1):29-36

Rezende VB, Barbosa F Jr, Montenegro MF, Sandrim VC, Gerlach RF, Tanus-Santos JE.

Genetic factors influence whole blood lead (Pb-B) concentrations in lead exposed subjects. This study aimed at examining the combined effects (haplotype analysis) of three polymorphisms (BsmI, ApaI and FokI) in vitamin D receptor (VDR) gene on Pb-B and on the concentrations of lead in plasma (Pb-P), which is more relevant to lead toxicity, in 150 environmentally exposed subjects.

O plástico ficou ecológico

Matérias-primas renováveis como cana-de-açúcar e milho são usadas para produzir plásticos menos agressivos ao meio ambiente



No tempo que você levará para ler esta reportagem, cerca de 50 000 sacolinhas plásticas serão consumidas no Brasil. A média nacional é de 1,5 milhão por hora. Embora representem pouco individualmente, os saquinhos de supermercado formam um volume enorme de lixo, que pode demorar vários séculos para se decompor no ambiente. Como reduzir o impacto causado pelo plástico na natureza é uma preocupação crescente. Por isso, ganham cada vez mais espaço as iniciativas de produzir plástico a partir de matérias-primas renováveis, como a cana- de-açúcar e o milho.

An interethnic comparison of the distribution of vitamin D receptor genotypes and haplotypes

 Clin Chim Acta 2007; 384(1-2):155-9


Rezende VB, Barbosa F Jr, Montenegro MF, Sandrim VC, Gerlach RF, Tanus-Santos JE.

BACKGROUND: The biological actions of vitamin D receptor (VDR) may be affected by genetic variations in the VDR gene. While there are interethnic differences in the frequency of VDR gene variants, there is little haplotype information, especially from admixed populations. We examined the distribution of genetic variants of 3 VDR polymorphisms (BsmI, ApaI and FokI) and haplotypes in black and white Brazilians. We have also compared our results with those from the HapMap project. METHODS: We studied 120 subjects